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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3805e6d7065d3256028b6ed95c3c27a07e35cf663884895a9880e6fa19cea63' 
  AND token = '/CSIivgYnToW6Rg+acA8dLSa9zfd03sayDztsx5CSW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}