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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aef1d104e4b907b2fb6e338f1b86688b027a898f7d0de5d1e82addc2884c6794' 
  AND token = 'ZTcPdCk8JpIotcv//SsydBOrXFhp1DWJKa4Ar/+PWSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}