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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ed8087e546ed73b4f54f2380f9db6ca16aa129cd43f97215d1e78f9346a6e47' 
  AND token = 'gC2v9SeZzc3DTkOrBIIsZgettscpjUZzlHSzLQ+9s7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}