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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b1d642fd9f2f4514c581e324afac84157a616ea9b001b7e049362a05fc58126' 
  AND token = '3zp/pSIPsRYuW50gICHEJ8QN0S0ITZwN0YpaFiJLmG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}