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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '264324df96df88437a5e4781e8b552e3caa7e694f8e5de18e15d4d6d9a3c6eca' 
  AND token = 'fJDfReq7c3I69PKJym15u+g3MYXrdDI5CTULoXb5cZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}