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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c49996d3439b9026182ee5358f452e924e69427bb437953bf3b806a8ea152b9' 
  AND token = 'VY1VrrmXgpXU4bd2zJRNTf4kTMb/svFwqIo2KsMjWig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}