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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65538a16a1b0d6daa0a76dc2885f4a15110b4f5a2fb5a44f6836bf5a90cadc37' 
  AND token = 'fq3BEqTN9flQzApSMb7WL5nxS+SIyxW0Xw27v4DAmHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}