SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ac2f6c41122f42287624d680a6fc7a6f9b4ca43f30a0d0e489541e538e2bcd7' 
  AND token = 'INt/lt1zCKyhSV15TsvtlUA5lpUjJjSvOCsWlyR3Tpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}