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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49274fcac0bc08674b6700e434b4687ca6a499627b6e963e7dd973d6ea730d14' 
  AND token = 'MnKPtfAaOyQtayik0AazxyseeU/y2vJJjhWiQM+elHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}