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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c51272056f150702ab2cc91964fc49c632e1399c487d262fe91e32b8a2a54819' 
  AND token = '+bpfjHwLEaTCfs28YacaFwyGKahsrcDNoFyJIbyvGiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}