SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c214e4d13709fe29418d44ff6bca782b3ce4a514d6007cbf9ec639016608c37' 
  AND token = 'siWuqw9jO8RR9//OObmmRJtUp3iPx0LaydrNmNU6LeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}