SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '599cb7caff65a6969a02a71a475a6f7aa3bf49eabcbd5128a5b1f002f0d6d555' 
  AND token = '40RqdeLsME/QXu8hvVGXmGWmfFD4qaxnTqjg7DfvFBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}