SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55ad612335b051af7c6dd426e476c1203fee54669548da2f13ee7cd965d1c2ac' 
  AND token = 'UbOVUy9ONR4adSX1+Sdgtj7fhFzcqUaRFpC1J6pJzj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}