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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b791eedca2d030d4649bfc9df7adc6cd3122ee025ab8006bae0f80b81b86449' 
  AND token = '5UQS2nBiiIsCABz1O5Q1+zCuM+WaMfgdUIhH7As5sy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}