SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449f0902f9bc0c18fb0b82e59f38cde5d62d677fc9c8d13e5d17b9e6d0df685d' 
  AND token = 'BCtrmjRwZKjh5NpXk7f9CpOLGY+x988xxDcH6Km4TCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00071

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}