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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '226d631634e4050c025b6857b5978b4b6f5d17d5ede8ca0b34fc0f1da4f2ed2f' 
  AND token = 'YLks3fIagauK6zm9NQHXBytdFhD9TugNhNN/SGoesK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}