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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a056a9d15216dd2771c1e2842ecbcff174d35985a9fcf82ab2ebc082a8e957c' 
  AND token = 'CrEu7Z+ev+7i4MTvkc4qjCVyybXa4WPY6RsEZBsySQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}