SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f5b25a50490da054f60a02c3b1ae4a4a267e822f267e9577d1cc2a3608c84e' 
  AND token = 'MLcjASdJeKMszIettme42eRD6NzwYsgmn05iDAt5ogg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}