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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b601786281b7398557aab2d90c0425d26418cb4e4e4ecd78476c21214f710a3b' 
  AND token = 'RrepnctMfp5no182ol/jWxVIVDk7cSHqV1V1V6/HOEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}