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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad82f9b074a297c169eab50f41a05268bb8fa4da73c4ba9be8625a9018729ee' 
  AND token = 'tb0F6664dIr6Wg6GhMfB6/Xlx9NWyQhRkroEOnW9A3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}