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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44a6b86afa84700918023762fb35a4246cc95a6ebe6c23f37ba1d6a600cea694' 
  AND token = '3MICMTBiEUqUFlzEgPEJo+TzjXG9IXXpF+UHn+HMpGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}