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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd605ccac832aed28aab18a421cd4222628ad876ce96e6b54681a36d0bbea64b1' 
  AND token = '/GfOz43VCq0mP/RZQwGobs8BGWGfep4B4c1qGg17ul8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}