SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a177b8683ca65272b1b776d3cec61a66bb0f153b000b8c130662a026e121e19f' 
  AND token = 'ibI/6HpB3d6qOEOvl2A36KLXJuiSxRq5FcD9FOuNy+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}