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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22421979fea98f7796e6022d85ee08dd2f8cc3d36bcbc2e3dc535ba6823edfc' 
  AND token = 'j+xqFaULhNYh9mr9Qabo+e+bgohjOm/icppX23zi+DA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}