SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d89aa040b9cab22091c803a78593373cd5848836677f6148c3f67dba912720c' 
  AND token = '3cPowKm38iRmy86+oLgAviycj2MGw1SRZHj/NPWk4aU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}