SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c0f3f322454aab2ab2ba621e8625bbd9f4af1839b5cd5f9edc3752dacbc6581' 
  AND token = 'VmOE9gxvWe/30QIWr5Qh6ocZTyiMderRQW0MAPVE3CI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}