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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0273c11b4ab450e557975379691d1be9394894d8d20d627f0cd3f59117ca0b5c' 
  AND token = 'f2V7GyY4t73vE3tdUrwQytWl4wR/+aP8OiNqYpC1XjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}