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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab64b7e6542c293dbed86940047b7ddb7c1f901948bdefd7031d792f647e2202' 
  AND token = 'OUwW6g4iYBss+INVz5SdVpR+POIC6yG2xhCj7DzCbRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}