SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ac301ec0f5ef7d7fd8a217490618cc662871bc5d2fc7903990608d13365a130' 
  AND token = 'Tyfl05VE5cFqN2+RfXcKenAnC7TH+oBESTQcWpyIkzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}