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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ed5802caee0ab9d443cc699f290d7a1c72d58cd7e2437b1021c65388e1d751a' 
  AND token = '+UIdJ/grlKJRiWdBEpnsJKJSxS9k0XevNk7RHDDSZWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}