SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c578003957e0f0d9c05f6df2c5192067df50d6fd46ca4b16dd1847752e507f01' 
  AND token = 'ni/A7IuY5/b9DbxvfhM3mwDtUYv++b7wadi5w4i/NKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}