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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7df329972ea92184c5bddbcda4a80fca745d810cb11fc6bca64365b6c9c7b5f4' 
  AND token = 'u8t3yQeO9wix3lRDtu3jTT0axkbQYYC+XNBfePz65Go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}