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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '384fcf2638181437c22de6c9ee58f6e2be036b1b2fa70771f89dbd0f5710ae2c' 
  AND token = 'cPOwC0So90beVH9Vr//vhIxsqYZry9Vhs/JKhlcQxs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}