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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acd1458012d21c3fef2f4b7340ee73d758ea2b651acd5895e25bfeecc976369d' 
  AND token = 'v+w46yIM1UMPiPPKeGtPrvKyINRIQO46AwQ7r8Xkcuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}