SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3371f784a4f5c7a7e39d54cfc903c4d3ecb8f6b1c32a7c7944e2e694941dac6b' 
  AND token = '6JxPFl9GJsFemVTmowDkZ/m1GVbwlt0qqMvm19+TBHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}