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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c81bbad8ce55a89d7a05ac5d43347c9bdf8464b00c470884dab3ac1ffa605a05' 
  AND token = 'S3PUw1g3MZK2VRuIIRflG1Yi3G+G6nqRgPmn9GVFjRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}