SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9458aa3bf6f4253219b28df582724a9b8cdd3ec5a5c7cb3426d3122f21a12fb7' 
  AND token = 'Rr0FwMq4sFHBHYq1/zu/kOWHKA9j64EpIJQ3dtkYq54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}