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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66c9756f1ae0457712e2655d4c61f8da1c8bbbc9dd72a85e3e99208dc6e9a246' 
  AND token = '6W9Il5s8lyXy3YGTRYa9eR/7V+DBjupRm6MwjjrnYSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}