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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e8886b8996a617c30bc9e3d5c93f3578c8e798ab9ac7335935287d59f868010' 
  AND token = 'zZyXI0SxGBnFpmBAITeoue45zyEjxhDkLIj/YXYWgg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}