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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ed48ac34da6b29b8b6a812a5bf0be721b29ba303c527c837e12726a8ae04992' 
  AND token = 'NLnHttCEFBF8XkxelFgdcytWvC8UmFbVa+0WhFUWXNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}