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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2b337f6ffbbfceb90e632fc4914e9ba3d3a2da8de7708a9e563efc35358b19a' 
  AND token = 'XSj5CzuKhz/IxVyti1lJtkU9DGxa5/Ls9hu9oKcdDcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}