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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b81f0bb600706cfe50170e3957c2a6d6f3d2df1299a1a4b2de4897270aee0d0' 
  AND token = 'tODTOi8HII61dmB7KE+OMQDcnA8JecabBjQ+rrOaGgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}