SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f03364255ae00a2d9dbe182fcb4e8a9c28b1dae2f27eb992e8af38435f50b60a' 
  AND token = 'CjsdEOk5l/+haEJKrXB/fkr5DwLZAOVIPyk0EQKDHIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}