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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d82e43784f13db33076328df5b049ed5cd55708ce61c3b15b0655c95de2288' 
  AND token = 'ZGGkUtZhqa2J2EwO9NUcp1wkE8+QLXIFWthd5yoRaUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}