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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f29a1c180f0ea477e05046b4b3133f505b6f8e5c83b55cb8ad0cbe21fa4135f' 
  AND token = 'SF0boLR0uxA17dkLQYCfW2gcGIrujRnsWkxlPYpaH4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}