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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3051fecc82194ec6bb0db48f1400aa0175f0a8fe15ce31be08c68d8018ab27a9' 
  AND token = 'AF9BIlXV97hQolc8PqgnX5xbgcuOaaQ5MDPuietzjbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}