SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad9fbc3ff2a71b4a100571774f1fd931efe00f6580e5bdc4c6f28fbd31970068' 
  AND token = '9HWlFcl2jTj58pjfC/QETc8HUmhRIpFSp50Hiac4Xq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}