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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '921c0a42dbca9493f7c7e3ed9d889c2f01ac33122234f05137c655d43623b2f2' 
  AND token = 'QcubnPT6zItAK76ZI9MTqvrxliKdRWiMrNDpcJvJ8BU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}