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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89f0d638814c707e5e5d15f6846b786cf72e12a6e6c509f48c761628ea206645' 
  AND token = 't5DUf8vcbEEpsQuvjtiTJfYJYcMUPjqIbhp3DA5IXdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}