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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfcce1166296476f6d1cc0b8bfde49d27665b042360dbc7d4f644bf051dc0779' 
  AND token = 'DReN+C+I5hf25ucx3utMCHphK8zGTR67qYd9Ofn23oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}